Biohacking: Human Growth Hormone
HDH Deficiency leads to higher fat
"HGH is a hormone made by the pituitary gland (the master gland). It plays a huge role in the normal development of children and adolescents as the name implies. However, it also plays a role in adults. HGH deficiency in adults typically leads to higher levels of body fat, lower lean body mass and decreased bone mass (osteopenia)."
Fasting. Loss of lean mass? No, likely an increase.
"Like cortisol, HGH increases glucose and thus is suppressed during feeding. Fasting is a great stimulus.
During fasting, there is the spike in the early morning, but there is regular secretion throughout the day as well. Hartman et al also showed a 5 fold increase in HGH in response to a 2 day fast.
This HGH is crucial in the maintenance of lean mass – both muscle and bone. One of the major concerns about fasting is the loss of lean mass. This does not occur. In fact, the opposite happens – there is likely an increase in lean mass."